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Volume 9 (2012) - July 2012

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Research   Open Access

Peroxisome proliferator-activated receptors γ/mitochondrial uncoupling protein 2 signaling protects against seizure-induced neuronal cell death in the hippocampus following experimental status epilepticus

Yao-Chung Chuang, Tsu-Kung Lin, Hsuan-Ying Huang, Wen-Neng Chang, Chia-Wei Liou, Shang-Der Chen, Alice YW Chang, Samuel HH Chan Journal of Neuroinflammation 2012, 9:184 (31 July 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Effects of anti-inflammatory vagus nerve stimulation on the cerebral microcirculation in endotoxinemic rats

Stanka Mihaylova, Anke Killian, Konstantin Mayer, Soni Pullamsetti, Ralph Schermuly, Bernhard Rosengarten Journal of Neuroinflammation 2012, 9:183 (25 July 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Recurrent/moderate hypoglycemia induces hippocampal dendritic injury, microglial activation, and cognitive impairment in diabetic rats

Seok Won, Byung Yoo, Tiina M Kauppinen, Bo Choi, Jin Kim, Bong Jang, Min Lee, Min Sohn, Jialing Liu, Raymond A Swanson, Sang Suh Journal of Neuroinflammation 2012, 9:182 (25 July 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Keratinocyte expression of inflammatory mediators plays a crucial role in substance P-induced acute and chronic pain

Tzuping Wei, Tian-Zhi Guo, Wen-Wu Li, Saiyun Hou, Wade S Kingery, John Clark Journal of Neuroinflammation 2012, 9:181 (23 July 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

The persistent release of HMGB1 contributes to tactile hyperalgesia in a rodent model of neuropathic pain

Polina Feldman, Michael R Due, Matthew S Ripsch, Rajesh Khanna, Fletcher A White Journal of Neuroinflammation 2012, 9:180 (23 July 2012)

Abstract | Full text | PDF | ePUB | PubMed

Research   Open Access Highly Accessed

Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study

David H Cribbs, Nicole C Berchtold, Victoria Perreau, Paul D Coleman, Joseph Rogers, Andrea J Tenner, Carl W Cotman Journal of Neuroinflammation 2012, 9:179 (23 July 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research   Open Access

Inhibition of EGFR/MAPK signaling reduces microglial inflammatory response and the associated secondary damage in rats after spinal cord injury

Wen-sheng Qu, Dai-shi Tian, Zhi-bao Guo, Jun Fang, Qiang Zhang, Zhi-yuan Yu, Min-jie Xie, Hua-qiu Zhang, Jia-gao Lü, Wei Wang Journal of Neuroinflammation 2012, 9:178 (23 July 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

C/EBPβ regulates multiple IL-1β-induced human astrocyte inflammatory genes

Jerel Fields, Anuja Ghorpade Journal of Neuroinflammation 2012, 9:177 (20 July 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access Highly Accessed

Acute injury in the peripheral nervous system triggers an alternative macrophage response

Elke Ydens, Anje Cauwels, Bob Asselbergh, Sofie Goethals, Lieve Peeraer, Guillaume Lornet, Leonardo Almeida-Souza, Jo A Van Ginderachter, Vincent Timmerman, Sophie Janssens Journal of Neuroinflammation 2012, 9:176 (20 July 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access Highly Accessed

JNK signaling is the shared pathway linking neuroinflammation, blood–brain barrier disruption, and oligodendroglial apoptosis in the white matter injury of the immature brain

Lan-Wan Wang, Yi-Fang Tu, Chao-Ching Huang, Chien-Jung Ho Journal of Neuroinflammation 2012, 9:175 (17 July 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Downstream Toll-like receptor signaling mediates adaptor-specific cytokine expression following focal cerebral ischemia

Bolanle Famakin, Yongshan Mou, Maria Spatz, Modinat Lawal, John Hallenbeck Journal of Neuroinflammation 2012, 9:174 (16 July 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access Highly Accessed

CD137 ligand activated microglia induces oligodendrocyte apoptosis via reactive oxygen species

Yee Yeo, Julia M Martínez Gómez, J Croxford, Stephan Gasser, Eng-Ang Ling, Herbert Schwarz Journal of Neuroinflammation 2012, 9:173 (16 July 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

P2X7 signaling promotes microsphere embolism-triggered microglia activation by maintaining elevation of Fas ligand

Ying-mei Lu, Rong-rong Tao, Ji-yun Huang, Li-tao Li, Mei-hua Liao, Xiao-ming Li, Kohji Fukunaga, Ze-Hui Hong, Feng Han Journal of Neuroinflammation 2012, 9:172 (12 July 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

The CCL2 synthesis inhibitor bindarit targets cells of the neurovascular unit, and suppresses experimental autoimmune encephalomyelitis

Shujun Ge, Bandana Shrestha, Debayon Paul, Carolyn Keating, Robert Cone, Angelo Guglielmotti, Joel S Pachter Journal of Neuroinflammation 2012, 9:171 (12 July 2012)

Abstract | Full text | PDF | ePUB | PubMed

Research   Open Access

Regulatory effects of the JAK3/STAT1 pathway on the release of secreted phospholipase A2-IIA in microvascular endothelial cells of the injured brain

Guansong Wang, Pin Qian, Zhi Xu, Jiqiang Zhang, Yaoli Wang, Saiyu Cheng, Wenqin Cai, Guisheng Qian, Changzheng Wang, Mark A DeCoster Journal of Neuroinflammation 2012, 9:170 (12 July 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Delayed expression of cell cycle proteins contributes to astroglial scar formation and chronic inflammation after rat spinal cord contusion

Junfang Wu, Ahdeah Pajoohesh-Ganji, Bogdan A Stoica, Michael Dinizo, Kelsey Guanciale, Alan I Faden Journal of Neuroinflammation 2012, 9:169 (11 July 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Pre-infection physical exercise decreases mortality and stimulates neurogenesis in bacterial meningitis

David Liebetanz, Joachim Gerber, Christina Schiffner, Sandra Schütze, Florian Klinker, Hubertus Jarry, Roland Nau, Simone C Tauber Journal of Neuroinflammation 2012, 9:168 (10 July 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access Highly Accessed

Intravenous immunoglobulin treatment of the post-polio syndrome: sustained effects on quality of life variables and cytokine expression after one year follow up

Henrik Gonzalez, Mohsen Khademi, Kristian Borg, Tomas Olsson Journal of Neuroinflammation 2012, 9:167 (9 July 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Complement receptor-3 negatively regulates the phagocytosis of degenerated myelin through tyrosine kinase Syk and cofilin

Smadar Hadas, Maya Spira, Uwe-Karsten Hanisch, Fanny Reichert, Shlomo Rotshenker Journal of Neuroinflammation 2012, 9:166 (9 July 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Inhibition of CD200R1 expression by C/EBP beta in reactive microglial cells

Guido Dentesano, Marco Straccia, Aroa Ejarque-Ortiz, Josep M Tusell, Joan Serratosa, Josep Saura, Carme Solà Journal of Neuroinflammation 2012, 9:165 (9 July 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Time-dependent effects of hypothermia on microglial activation and migration

Jung-Wan Seo, Jong-Heon Kim, Jae-Hong Kim, Minchul Seo, Hyung Han, Jaechan Park, Kyoungho Suk Journal of Neuroinflammation 2012, 9:164 (9 July 2012)

Abstract | Full text | PDF | ePUB | PubMed

Research   Open Access Highly Accessed

Effects of dimethyl fumarate on neuroprotection and immunomodulation

Philipp Albrecht, Imane Bouchachia, Norbert Goebels, Nadine Henke, Harald H Hofstetter, Andrea Issberner, Zsuzsa Kovacs, Jan Lewerenz, Dmitrij Lisak, Pamela Maher, Anne-Kathrin Mausberg, Kim Quasthoff, Corinna Zimmermann, Hans-Peter Hartung, Axel Methner Journal of Neuroinflammation 2012, 9:163 (7 July 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Association of inflammatory gene polymorphisms with ischemic stroke in a Chinese Han population

Nan Zhao, Xin Liu, Yongqin Wang, Xiaoqiu Liu, Jiana Li, Litian Yu, Liyuan Ma, Shuyu Wang, Hongye Zhang, Lisheng Liu, Jingbo Zhao, Xingyu Wang Journal of Neuroinflammation 2012, 9:162 (6 July 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access Highly Accessed

(−)-Epigallocatechin gallate inhibits endotoxin-induced expression of inflammatory cytokines in human cerebral microvascular endothelial cells

Jieliang Li, Li Ye, Xu Wang, Jinping Liu, Yizhong Wang, Yu Zhou, Wenzhe Ho Journal of Neuroinflammation 2012, 9:161 (6 July 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Case report   Open Access

Cytotoxic CD8+ T cells and CD138+ plasma cells prevail in cerebrospinal fluid in non-paraneoplastic cerebellar ataxia with contactin-associated protein-2 antibodies

Nico Melzer, Kristin S Golombeck, Catharina C Gross, Sven G Meuth, Heinz Wiendl Journal of Neuroinflammation 2012, 9:160 (3 July 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Inflammation modulates expression of laminin in the central nervous system following ischemic injury

Kyungmin Ji, Stella E Tsirka Journal of Neuroinflammation 2012, 9:159 (3 July 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access Highly Accessed

Elevated serum levels of interleukin-17A in children with autism

Laila AL-Ayadhi, Gehan Mostafa Journal of Neuroinflammation 2012, 9:158 (2 July 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Post-ischemic estradiol treatment reduced glial response and triggers distinct cortical and hippocampal signaling in a rat model of cerebral ischemia

Maria Pérez-Álvarez, Maria del Maza, Marta Anton, Lara Ordoñez, Francisco Wandosell Journal of Neuroinflammation 2012, 9:157 (2 July 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Clusters of activated microglia in normal-appearing white matter show signs of innate immune activation

Jack van Horssen, Shailender Singh, Susanne van der Pol, Markus Kipp, Jamie L Lim, Laura Peferoen, Wouter Gerritsen, Evert-Jan Kooi, Maarten E Witte, Jeroen JG Geurts, Helga E de Vries, Regina Peferoen-Baert, Peter J van den Elsen, Paul van der Valk, Sandra Amor Journal of Neuroinflammation 2012, 9:156 (2 July 2012)

Abstract | Full text | PDF | PubMed

Review   Open Access Highly Accessed

Neuroimmune crosstalk in the central nervous system and its significance for neurological diseases

Li Tian, Li Ma, Tiina Kaarela, Zhilin Li Journal of Neuroinflammation 2012, 9:155 (2 July 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Secreted phospholipase A2-IIA-induced a phenotype of activated microglia in BV-2 cells requires epidermal growth factor receptor transactivation and proHB-EGF shedding

Rubén Martín, Claudia Cordova, Maria L Nieto Journal of Neuroinflammation 2012, 9:154 (2 July 2012)

Abstract | Full text | PDF | ePUB | PubMed

Research   Open Access

The enteric bacterial metabolite propionic acid alters brain and plasma phospholipid molecular species: further development of a rodent model of autism spectrum disorders

Raymond H Thomas, Melissa M Meeking, Jennifer R Mepham, Lisa Tichenoff, Fred Possmayer, Suya Liu, Derrick F MacFabe Journal of Neuroinflammation 2012, 9:153 (2 July 2012)

Abstract | Full text | PDF | ePUB | PubMed | Cited on BioMed Central

Research   Open Access

c-Src-dependent EGF receptor transactivation contributes to ET-1-induced COX-2 expression in brain microvascular endothelial cells

Hsi-Lung Hsieh, Chih-Chung Lin, Hui-Ju Chan, Caleb M Yang, Chuen-Mao Yang Journal of Neuroinflammation 2012, 9:152 (2 July 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research   Open Access Highly Accessed

Systemic immune challenges trigger and drive Alzheimer-like neuropathology in mice

Dimitrije Krstic, Amrita Madhusudan, Jana Doehner, Prisca Vogel, Tina Notter, Claudine Imhof, Abigail Manalastas, Martina Hilfiker, Sandra Pfister, Cornelia Schwerdel, Carsten Riether, Urs Meyer, Irene Knuesel Journal of Neuroinflammation 2012, 9:151 (2 July 2012)

Abstract | Full text | PDF | ePUB | PubMed | 1 comment | F1000 Biology |  Editor’s summary

A systemic immune challenge during a late gestational window has a detrimental and long-term effect on cognitive performance during adulthood and aging, proposing a link between disturbances of late embryonic development and risk of Alzheimer-like neuropathology.


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