Figure 3.

Relative size distributions of lymph cells in the spleen of control and calorie-restricted rats. CD4⁺, CD8⁺, CD4⁺-CD8⁺, T, B and T-B lymphocytes, as well as CD4⁺/CD8⁺ and T/B ratios, were measured as described in Materials and methods. Data shown as mean ± SEM (n = 7 rats/group). Letters indicate the existence of significant differences between groups after a one-way ANOVA followed by a Bonferroni's test, as follows: ^a p < 0.05 vs. control and 33% calorie-restricted rats, neither injected with SCH; ^b p < 0.02 vs. control and 33% calorie-restricted rats, neither injected with SCH; ^c p < 0.02 vs. 33% calorie-restricted rats not injected with SCH; ^d p < 0.02 vs. control and 33% calorie-restricted rats regardless of SCH injection; ^e p < 0.02 vs. 66% calorie-restricted rats not injected with SCH; ^f p < 0.01 vs. 66% calorie-restricted rats regardless of SCH injection; ^g p < 0.03 vs. control and 33% calorie-restricted rats, both injected with SCH; ^h p < 0.01 vs. all groups. For further statistical analysis, see text.