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Total Aβ load is significantly reduced following 5 months of anti-Aβ antibody treatment. Percent area occupied by positive immunohistochemical stain for Aβ is shown ± standard error of the mean for both the frontal cortex and hippocampus. Also shown is the percent reduction of Aβ observed following anti-Aβ antibody treatment |
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| Region |
% area positive for Aβ: control treated |
% area positive for Aβ: anti-Aβ treated |
% reduction following anti-Aβ antibody treatment |
|
|
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| Frontal Cortex |
34.855 ± 2.265 |
9.681 ± 0.754 |
72 |
| Hippocampus |
23.994 ± 0.985 |
8.212 ± 0.596 |
66 |
Wilcock et al. Journal of Neuroinflammation 2004 1:24 doi:10.1186/1742-2094-1-24 |
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