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Items 1 - 20 of 174
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1:
Zhang D, Hu X, Wei SJ, Liu J, Gao H, Qian L, Wilson B, Liu G, Hong JS.
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Squamosamide derivative FLZ protects dopaminergic neurons against inflammation-mediated neurodegeneration through the inhibition of NADPH oxidase activity.
J Neuroinflammation. 2008 May 28;5:21.
PMID: 18507839 [PubMed - indexed for MEDLINE]
2:
Qian L, Xu Z, Zhang W, Wilson B, Hong JS, Flood PM.
Free in PMC
Sinomenine, a natural dextrorotatory morphinan analog, is anti-inflammatory and neuroprotective through inhibition of microglial NADPH oxidase.
J Neuroinflammation. 2007 Sep 19;4:23.
PMID: 17880684 [PubMed - indexed for MEDLINE]
3:
Zhang W, Qin L, Wang T, Wei SJ, Gao HM, Liu J, Wilson B, Liu B, Zhang W, Kim HC, Hong JS.
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3-hydroxymorphinan is neurotrophic to dopaminergic neurons and is also neuroprotective against LPS-induced neurotoxicity.
FASEB J. 2005 Mar;19(3):395-7. Epub 2004 Dec 13.
PMID: 15596482 [PubMed - indexed for MEDLINE]
4:
Liu Y, Qin L, Li G, Zhang W, An L, Liu B, Hong JS.
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Dextromethorphan protects dopaminergic neurons against inflammation-mediated degeneration through inhibition of microglial activation.
J Pharmacol Exp Ther. 2003 Apr;305(1):212-8.
PMID: 12649371 [PubMed - indexed for MEDLINE]
5:
Qian L, Block ML, Wei SJ, Lin CF, Reece J, Pang H, Wilson B, Hong JS, Flood PM.
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Interleukin-10 protects lipopolysaccharide-induced neurotoxicity in primary midbrain cultures by inhibiting the function of NADPH oxidase.
J Pharmacol Exp Ther. 2006 Oct;319(1):44-52. Epub 2006 Jun 28.
PMID: 16807359 [PubMed - indexed for MEDLINE]
6:
Qin L, Liu Y, Wang T, Wei SJ, Block ML, Wilson B, Liu B, Hong JS.
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NADPH oxidase mediates lipopolysaccharide-induced neurotoxicity and proinflammatory gene expression in activated microglia.
J Biol Chem. 2004 Jan 9;279(2):1415-21. Epub 2003 Oct 24.
PMID: 14578353 [PubMed - indexed for MEDLINE]
7:
Qian L, Wei SJ, Zhang D, Hu X, Xu Z, Wilson B, El-Benna J, Hong JS, Flood PM.
Abstract
Potent anti-inflammatory and neuroprotective effects of TGF-beta1 are mediated through the inhibition of ERK and p47phox-Ser345 phosphorylation and translocation in microglia.
J Immunol. 2008 Jul 1;181(1):660-8.
PMID: 18566433 [PubMed - indexed for MEDLINE]
8:
Li G, Cui G, Tzeng NS, Wei SJ, Wang T, Block ML, Hong JS.
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Femtomolar concentrations of dextromethorphan protect mesencephalic dopaminergic neurons from inflammatory damage.
FASEB J. 2005 Apr;19(6):489-96.
PMID: 15790998 [PubMed - indexed for MEDLINE]
9:
Tran TA, McCoy MK, Sporn MB, Tansey MG.
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The synthetic triterpenoid CDDO-methyl ester modulates microglial activities, inhibits TNF production, and provides dopaminergic neuroprotection.
J Neuroinflammation. 2008 May 12;5:14.
PMID: 18474101 [PubMed - indexed for MEDLINE]
10:
Yang S, Yang J, Yang Z, Chen P, Fraser A, Zhang W, Pang H, Gao X, Wilson B, Hong JS, Block ML.
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Pituitary adenylate cyclase-activating polypeptide (PACAP) 38 and PACAP4-6 are neuroprotective through inhibition of NADPH oxidase: potent regulators of microglia-mediated oxidative stress.
J Pharmacol Exp Ther. 2006 Nov;319(2):595-603. Epub 2006 Aug 4.
PMID: 16891616 [PubMed - indexed for MEDLINE]
11:
Gao HM, Liu B, Hong JS.
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Critical role for microglial NADPH oxidase in rotenone-induced degeneration of dopaminergic neurons.
J Neurosci. 2003 Jul 16;23(15):6181-7.
PMID: 12867501 [PubMed - indexed for MEDLINE]
12:
Qin L, Liu Y, Qian X, Hong JS, Block ML.
Abstract
Microglial NADPH oxidase mediates leucine enkephalin dopaminergic neuroprotection.
Ann N Y Acad Sci. 2005 Aug;1053:107-20.
PMID: 16179514 [PubMed - indexed for MEDLINE]
13:
Qian L, Tan KS, Wei SJ, Wu HM, Xu Z, Wilson B, Lu RB, Hong JS, Flood PM.
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Microglia-mediated neurotoxicity is inhibited by morphine through an opioid receptor-independent reduction of NADPH oxidase activity.
J Immunol. 2007 Jul 15;179(2):1198-209.
PMID: 17617613 [PubMed - indexed for MEDLINE]
14:
Tian YY, An LJ, Jiang L, Duan YL, Chen J, Jiang B.
Abstract
Catalpol protects dopaminergic neurons from LPS-induced neurotoxicity in mesencephalic neuron-glia cultures.
Life Sci. 2006 Dec 23;80(3):193-9. Epub 2006 Sep 20.
PMID: 17049947 [PubMed - indexed for MEDLINE]
15:
Gao X, Hu X, Qian L, Yang S, Zhang W, Zhang D, Wu X, Fraser A, Wilson B, Flood PM, Block M, Hong JS.
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Formyl-methionyl-leucyl-phenylalanine-induced dopaminergic neurotoxicity via microglial activation: a mediator between peripheral infection and neurodegeneration?
Environ Health Perspect. 2008 May;116(5):593-8.
PMID: 18470306 [PubMed - indexed for MEDLINE]
16:
Peng GS, Li G, Tzeng NS, Chen PS, Chuang DM, Hsu YD, Yang S, Hong JS.
Abstract
Valproate pretreatment protects dopaminergic neurons from LPS-induced neurotoxicity in rat primary midbrain cultures: role of microglia.
Brain Res Mol Brain Res. 2005 Mar 24;134(1):162-9. Epub 2004 Nov 25.
PMID: 15790540 [PubMed - indexed for MEDLINE]
17:
Qin L, Liu Y, Cooper C, Liu B, Wilson B, Hong JS.
Abstract
Microglia enhance beta-amyloid peptide-induced toxicity in cortical and mesencephalic neurons by producing reactive oxygen species.
J Neurochem. 2002 Nov;83(4):973-83.
PMID: 12421370 [PubMed - indexed for MEDLINE]
18:
Zhang W, Wang T, Qin L, Gao HM, Wilson B, Ali SF, Zhang W, Hong JS, Liu B.
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Neuroprotective effect of dextromethorphan in the MPTP Parkinson's disease model: role of NADPH oxidase.
FASEB J. 2004 Mar;18(3):589-91. Epub 2004 Jan 20.
PMID: 14734632 [PubMed - indexed for MEDLINE]
19:
Feng W, Wei H, Liu GT.
Abstract
Pharmacological study of the novel compound FLZ against experimental Parkinson's models and its active mechanism.
Mol Neurobiol. 2005;31(1-3):295-300. Review.
PMID: 15953829 [PubMed - indexed for MEDLINE]
20:
Li FQ, Wang T, Pei Z, Liu B, Hong JS.
Abstract
Inhibition of microglial activation by the herbal flavonoid baicalein attenuates inflammation-mediated degeneration of dopaminergic neurons.
J Neural Transm. 2005 Mar;112(3):331-47. Epub 2004 Oct 22.
PMID: 15503194 [PubMed - indexed for MEDLINE]
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