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Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia.
Henry CJ, Huang Y, Wynne A, Hanke M, Himler J, Bailey MT, Sheridan JF, Godbout JP.
J Neuroinflammation. 2008 May 13;5:15.
PMID: 18477398 [PubMed - indexed for MEDLINE]
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Peripheral lipopolysaccharide (LPS) challenge promotes microglial hyperactivity in aged mice that is associated with exaggerated induction of both pro-inflammatory IL-1beta and anti-inflammatory IL-10 cytokines.
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Brain Behav Immun. 2008 Sep 12. [Epub ahead of print]
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