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1.

1650
Accesses

Review   Open Access Highly Accessed

Neuroinflammation and psychiatric illness

Souhel Najjar, Daniel M Pearlman, Kenneth Alper, Amanda Najjar, Orrin Devinsky Journal of Neuroinflammation 2013, 10:43 (1 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

2.

825
Accesses

Review   Open Access Highly Accessed

Focal brain inflammation and autism

Theoharis C Theoharides, Shahrzad Asadi, Arti B Patel Journal of Neuroinflammation 2013, 10:46 (9 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

3.

808
Accesses

Research   Open Access

Analysis of inflammation-related nigral degeneration and locomotor function in DJ-1 −/− mice

Thi A Nguyen, Tamy Frank-Cannon, Terina N Martinez, Kelly A Ruhn, Marian Marvin, Bradford Casey, Isaac Treviño, John J Hong, Matthew S Goldberg, Malú G Tansey Journal of Neuroinflammation 2013, 10:50 (28 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

4.

751
Accesses

Review   Open Access Highly Accessed

A comparative review of cell culture systems for the study of microglial biology in Alzheimer’s disease

Branden Stansley, Jan Post, Kenneth Hensley Journal of Neuroinflammation 2012, 9:115 (31 May 2012)

Abstract | Full text | PDF | PubMed

5.

718
Accesses

Review   Open Access Highly Accessed

Alzheimer's disease - a neurospirochetosis. Analysis of the evidence following Koch's and Hill's criteria

Judith Miklossy Journal of Neuroinflammation 2011, 8:90 (4 August 2011)

Abstract | Full text | PDF | PubMed | F1000 Biology

6.

683
Accesses

Research   Open Access Highly Accessed

Persisting atypical and cystic forms of Borrelia burgdorferi and local inflammation in Lyme neuroborreliosis

Judith Miklossy, Sandor Kasas, Anne D Zurn, Sherman McCall, Sheng Yu, Patrick L McGeer Journal of Neuroinflammation 2008, 5:40 (25 September 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

7.

671
Accesses

Research   Open Access

Differential expression of interferon-γ and chemokine genes distinguishes Rasmussen encephalitis from cortical dysplasia and provides evidence for an early Th1 immune response

Geoffrey C Owens, My N Huynh, Julia W Chang, David L McArthur, Michelle J Hickey, Harry V Vinters, Gary W Mathern, Carol A Kruse Journal of Neuroinflammation 2013, 10:56 (2 May 2013)

Abstract | Full text | PDF | PubMed

8.

645
Accesses

Research   Open Access

Exercise-induced hippocampal anti-inflammatory response in aged rats

Sérgio Gomes da Silva, Priscila Santos Simões, Renato Mortara, Fulvio Scorza, Esper Cavalheiro, Maria da Graça Naffah-Mazzacoratti, Ricardo Arida Journal of Neuroinflammation 2013, 10:61 (10 May 2013)

Abstract | Full text | PDF | PubMed

9.

583
Accesses

Research   Open Access

Preventive immunization of aged and juvenile non-human primates to beta-amyloid

Julia Kofler, Brian Lopresti, Chris Janssen, Anita M Trichel, Eliezer Masliah, Olivera J Finn, Russell D Salter, Geoffrey H Murdoch, Chester A Mathis, Clayton A Wiley Journal of Neuroinflammation 2012, 9:84 (3 May 2012)

Abstract | Full text | PDF | PubMed

10.

574
Accesses

Review   Open Access Highly Accessed

TNF-α and neuropathic pain - a review

Lawrence Leung, Catherine M Cahill Journal of Neuroinflammation 2010, 7:27 (16 April 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

11.

571
Accesses

Research   Open Access Highly Accessed

Effects of dimethyl fumarate on neuroprotection and immunomodulation

Philipp Albrecht, Imane Bouchachia, Norbert Goebels, Nadine Henke, Harald H Hofstetter, Andrea Issberner, Zsuzsa Kovacs, Jan Lewerenz, Dmitrij Lisak, Pamela Maher, Anne-Kathrin Mausberg, Kim Quasthoff, Corinna Zimmermann, Hans-Peter Hartung, Axel Methner Journal of Neuroinflammation 2012, 9:163 (7 July 2012)

Abstract | Full text | PDF | PubMed

12.

553
Accesses

Research   Open Access Highly Accessed

Macrophages in inflammatory multiple sclerosis lesions have an intermediate activation status

Daphne YS Vogel, Elly JF Vereyken, Judith E Glim, Priscilla DAM Heijnen, Martina Moeton, Paul van der Valk, Sandra Amor, Charlotte E Teunissen, Jack van Horssen, Christine D Dijkstra Journal of Neuroinflammation 2013, 10:35 (4 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

13.

540
Accesses

Research   Open Access

Acute and subacute IL-1β administrations differentially modulate neuroimmune and neurotrophic systems: possible implications for neuroprotection and neurodegeneration

Cai Song, Ye Zhang, Yilong Dong Journal of Neuroinflammation 2013, 10:59 (7 May 2013)

Abstract | Full text | PDF | PubMed

14.

520
Accesses

Research   Open Access

Interleukin-1 beta converting enzyme is necessary for development of depression-like behavior following intracerebroventricular administration of lipopolysaccharide to mice

Marcus A Lawson, Robert H McCusker, Keith W Kelley Journal of Neuroinflammation 2013, 10:54 (1 May 2013)

Abstract | Provisional PDF | PubMed

15.

517
Accesses

Research   Open Access

Brucella abortus induces TNF-α-dependent astroglial MMP-9 secretion through mitogen-activated protein kinases

M Cruz Miraglia, Romina Scian, Clara García Samartino, Paula Barrionuevo, Ana M Rodriguez, Andrés E Ibañez, Lorena M Coria, Lis N Velásquez, Pablo C Baldi, Juliana Cassataro, M Victoria Delpino, Guillermo H Giambartolomei Journal of Neuroinflammation 2013, 10:47 (12 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

16.

510
Accesses

Short report   Open Access

Poly(ADP-ribose) polymerase 2 contributes to neuroinflammation and neurological dysfunction in mouse experimental autoimmune encephalomyelitis

Amit Kamboj, Ping Lu, Michael B Cossoy, Jillian L Stobart, Brian A Dolhun, Tiina M Kauppinen, Gilbert de Murcia, Christopher M Anderson Journal of Neuroinflammation 2013, 10:49 (22 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

17.

510
Accesses

Research   Open Access

Human marrow stromal cells reduce microglial activation to protect motor neurons in a transgenic mouse model of amyotrophic lateral sclerosis

Chang Zhou, Chen Zhang, Renliang Zhao, Song Chi, Ping Ge, Cheng Zhang Journal of Neuroinflammation 2013, 10:52 (30 April 2013)

Abstract | Full text | PDF | PubMed

18.

502
Accesses

Case report   Open Access Highly Accessed

Rapid cognitive improvement in Alzheimer's disease following perispinal etanercept administration

Edward L Tobinick, Hyman Gross Journal of Neuroinflammation 2008, 5:2 (9 January 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology |  Editor’s summary

Report of rapid cognitive improvement in an Alzheimer's patient within minutes following delivery of an anti-tumor necrosis factor-alpha (TNF) therapeutic, etanercept.

19.

494
Accesses

Research   Open Access

Cognitive and cerebrovascular improvements following kinin B1 receptor blockade in Alzheimer's disease mice

Baptiste Lacoste, Xin-Kang Tong, Karim Lahjouji, Réjean Couture, Edith Hamel Journal of Neuroinflammation 2013, 10:57 (4 May 2013)

Abstract | Provisional PDF | PubMed

20.

488
Accesses

Research   Open Access Highly Accessed

Toll-like receptor 4 mediates microglial activation and production of inflammatory mediators in neonatal rat brain following hypoxia: role of TLR4 in hypoxic microglia

Linli Yao, Enci Mary Kan, Jia Lu, Aijun Hao, S Thameem Dheen, Charanjit Kaur, Eng-Ang Ling Journal of Neuroinflammation 2013, 10:23 (6 February 2013)

Abstract | Full text | PDF | ePUB | PubMed

21.

486
Accesses

Research   Open Access Highly Accessed

Systemic immune challenges trigger and drive Alzheimer-like neuropathology in mice

Dimitrije Krstic, Amrita Madhusudan, Jana Doehner, Prisca Vogel, Tina Notter, Claudine Imhof, Abigail Manalastas, Martina Hilfiker, Sandra Pfister, Cornelia Schwerdel, Carsten Riether, Urs Meyer, Irene Knuesel Journal of Neuroinflammation 2012, 9:151 (2 July 2012)

Abstract | Full text | PDF | ePUB | PubMed | 1 comment | F1000 Biology |  Editor’s summary

A systemic immune challenge during a late gestational window has a detrimental and long-term effect on cognitive performance during adulthood and aging, proposing a link between disturbances of late embryonic development and risk of Alzheimer-like neuropathology.

22.

481
Accesses

Research   Open Access

Microglial activation decreases retention of the protease inhibitor saquinavir: implications for HIV treatment

Shannon Dallas, Michelle L Block, Deborah M Thompson, Marcelo G Bonini, Patrick T Ronaldson, Reina Bendayan, David S Miller Journal of Neuroinflammation 2013, 10:58 (4 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

23.

468
Accesses

Review   Open Access Highly Accessed

Wallerian degeneration: gaining perspective on inflammatory events after peripheral nerve injury

Andrew D Gaudet, Phillip G Popovich, Matt S Ramer Journal of Neuroinflammation 2011, 8:110 (30 August 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

24.

468
Accesses

Review   Open Access Highly Accessed

TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease

Melissa K McCoy, Malú G Tansey Journal of Neuroinflammation 2008, 5:45 (17 October 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

25.

448
Accesses

Hypothesis   Open Access Highly Accessed

Neuro-inflammation, blood-brain barrier, seizures and autism

Theoharis C Theoharides, Bodi Zhang Journal of Neuroinflammation 2011, 8:168 (30 November 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

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