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Research   Open Access

Innate immunity in the Grid2 Lc/+ mouse model of cerebellar neurodegeneration: glial CD95/CD95L plays a non-apoptotic role in persistent neuron loss-associated inflammatory reactions in the cerebellum

Béatrice Vernet-der Garabedian, Paul Derer, Yannick Bailly, Jean Mariani Journal of Neuroinflammation 2013, 10:65 (15 May 2013)

Abstract | Full text | PDF | PubMed

Research   Open Access

Neurogenic factor-induced Langerhans cell activation in diabetic mice with mechanical allodynia

Jacqueline R Dauch, Diane E Bender, Lucía A Luna-Wong, Wilson Hsieh, Brandon M Yanik, Zachary A Kelly, Hsinlin T Cheng Journal of Neuroinflammation 2013, 10:64 (14 May 2013)

Abstract | Provisional PDF | PubMed

Research   Open Access

Delayed brain ischemia tolerance induced by electroacupuncture pretreatment is mediated via MCP-induced protein 1

Zhuqing Jin, Jian Liang, Jing Wang, Pappachan E Kolattukudy Journal of Neuroinflammation 2013, 10:63 (10 May 2013)

Abstract | Provisional PDF | PubMed

Research   Open Access

Cerebrospinal fluid neopterin decay characteristics after initiation of antiretroviral therapy

Aylin Yilmaz, Constantin T Yiannoutsos, Dietmar Fuchs, Richard W Price, Kathryn Crozier, Lars Hagberg, Serena Spudich, Magnus Gisslén Journal of Neuroinflammation 2013, 10:62 (10 May 2013)

Abstract | Full text | PDF | PubMed

Research   Open Access

Exercise-induced hippocampal anti-inflammatory response in aged rats

Sérgio Gomes da Silva, Priscila Santos Simões, Renato Mortara, Fulvio Scorza, Esper Cavalheiro, Maria da Graça Naffah-Mazzacoratti, Ricardo Arida Journal of Neuroinflammation 2013, 10:61 (10 May 2013)

Abstract | Full text | PDF | PubMed

Research   Open Access

Genetic variability in the rat Aplec C-type lectin gene cluster regulates lymphocyte trafficking and motor neuron survival after traumatic nerve root injury

Rickard PF Lindblom, Shahin Aeinehband, Roham Parsa, Mikael Ström, Faiez Al Nimer, Xing-Mei Zhang, Cecilia A Dominguez, Sevasti Flytzani, Margarita Diez, Fredrik Piehl Journal of Neuroinflammation 2013, 10:60 (8 May 2013)

Abstract | Provisional PDF | PubMed

Research   Open Access

Acute and subacute IL-1β administrations differentially modulate neuroimmune and neurotrophic systems: possible implications for neuroprotection and neurodegeneration

Cai Song, Ye Zhang, Yilong Dong Journal of Neuroinflammation 2013, 10:59 (7 May 2013)

Abstract | Full text | PDF | PubMed

Research   Open Access

Microglial activation decreases retention of the protease inhibitor saquinavir: implications for HIV treatment

Shannon Dallas, Michelle L Block, Deborah M Thompson, Marcelo G Bonini, Patrick T Ronaldson, Reina Bendayan, David S Miller Journal of Neuroinflammation 2013, 10:58 (4 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research   Open Access

Cognitive and cerebrovascular improvements following kinin B1 receptor blockade in Alzheimer's disease mice

Baptiste Lacoste, Xin-Kang Tong, Karim Lahjouji, Réjean Couture, Edith Hamel Journal of Neuroinflammation 2013, 10:57 (4 May 2013)

Abstract | Provisional PDF | PubMed

Research   Open Access

Differential expression of interferon-γ and chemokine genes distinguishes Rasmussen encephalitis from cortical dysplasia and provides evidence for an early Th1 immune response

Geoffrey C Owens, My N Huynh, Julia W Chang, David L McArthur, Michelle J Hickey, Harry V Vinters, Gary W Mathern, Carol A Kruse Journal of Neuroinflammation 2013, 10:56 (2 May 2013)

Abstract | Full text | PDF | PubMed

Research   Open Access

Bilateral elevation of interleukin-6 protein and mRNA in both lumbar and cervical dorsal root ganglia following unilateral chronic compression injury of the sciatic nerve

Petr Dubový, Václav Brázda, Ilona Klusáková, Ivana Hradilová-Svíženská Journal of Neuroinflammation 2013, 10:55 (1 May 2013)

Abstract | Full text | PDF | PubMed

Research   Open Access

Interleukin-1 beta converting enzyme is necessary for development of depression-like behavior following intracerebroventricular administration of lipopolysaccharide to mice

Marcus A Lawson, Robert H McCusker, Keith W Kelley Journal of Neuroinflammation 2013, 10:54 (1 May 2013)

Abstract | Provisional PDF | PubMed

Short report   Open Access

Hippocampal gene expression dysregulation of Klotho, nuclear factor kappa B and tumor necrosis factor in temporal lobe epilepsy patients

Marcelo Teocchi, Ana Érika Ferreira, Evandro da Luz de Oliveira, Helder Tedeschi, Lília D’Souza-Li Journal of Neuroinflammation 2013, 10:53 (1 May 2013)

Abstract | Full text | PDF | PubMed

Research   Open Access

Human marrow stromal cells reduce microglial activation to protect motor neurons in a transgenic mouse model of amyotrophic lateral sclerosis

Chang Zhou, Chen Zhang, Renliang Zhao, Song Chi, Ping Ge, Cheng Zhang Journal of Neuroinflammation 2013, 10:52 (30 April 2013)

Abstract | Full text | PDF | PubMed

Research   Open Access

Different actions of endothelin-1 on chemokine production in rat cultured astrocytes: reduction of CX3CL1/fractalkine and an increase in CCL2/MCP-1 and CXCL1/CINC-1

Yutaka Koyama, Mao Kotani, Tadateru Sawamura, Miho Kuribayashi, Rika Konishi, Shotaro Michinaga Journal of Neuroinflammation 2013, 10:51 (30 April 2013)

Abstract | Full text | PDF | PubMed

Research   Open Access

Analysis of inflammation-related nigral degeneration and locomotor function in DJ-1 −/− mice

Thi A Nguyen, Tamy Frank-Cannon, Terina N Martinez, Kelly A Ruhn, Marian Marvin, Bradford Casey, Isaac Treviño, John J Hong, Matthew S Goldberg, Malú G Tansey Journal of Neuroinflammation 2013, 10:50 (28 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

Short report   Open Access

Poly(ADP-ribose) polymerase 2 contributes to neuroinflammation and neurological dysfunction in mouse experimental autoimmune encephalomyelitis

Amit Kamboj, Ping Lu, Michael B Cossoy, Jillian L Stobart, Brian A Dolhun, Tiina M Kauppinen, Gilbert de Murcia, Christopher M Anderson Journal of Neuroinflammation 2013, 10:49 (22 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

Correction   Open Access

Correction: Microglial TIR-domain-containing adapter-inducing interferon-β (TRIF) deficiency promotes retinal ganglion cell survival and axon regeneration via nuclear factor-κB

Sen Lin, Yajie Liang, Jiqiang Zhang, Chen Bian, Hongli Zhou, Qiang Guo, Ying Xiong, Shurong Li, Bingyin Su Journal of Neuroinflammation 2013, 10:48 (19 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research   Open Access

Brucella abortus induces TNF-α-dependent astroglial MMP-9 secretion through mitogen-activated protein kinases

M Cruz Miraglia, Romina Scian, Clara García Samartino, Paula Barrionuevo, Ana M Rodriguez, Andrés E Ibañez, Lorena M Coria, Lis N Velásquez, Pablo C Baldi, Juliana Cassataro, M Victoria Delpino, Guillermo H Giambartolomei Journal of Neuroinflammation 2013, 10:47 (12 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

Review   Open Access Highly Accessed

Focal brain inflammation and autism

Theoharis C Theoharides, Shahrzad Asadi, Arti B Patel Journal of Neuroinflammation 2013, 10:46 (9 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research   Open Access

Celecoxib reduces brain dopaminergic neuronaldysfunction, and improves sensorimotor behavioral performance in neonatal rats exposed to systemic lipopolysaccharide

Asuka Kaizaki, Lu-Tai Tien, Yi Pang, Zhengwei Cai, Sachiko Tanaka, Satoshi Numazawa, Abhay J Bhatt, Lir-Wan Fan Journal of Neuroinflammation 2013, 10:45 (5 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research   Open Access

Traumatic axonal injury in the mouse is accompanied by a dynamic inflammatory response, astroglial reactivity and complex behavioral changes

Sara Ekmark-Lewén, Johanna Flygt, Olivia Kiwanuka, Bengt J Meyerson, Anders Lewén, Lars Hillered, Niklas Marklund Journal of Neuroinflammation 2013, 10:44 (4 April 2013)

Abstract | Full text | PDF | PubMed | F1000 Biology

Review   Open Access Highly Accessed

Neuroinflammation and psychiatric illness

Souhel Najjar, Daniel M Pearlman, Kenneth Alper, Amanda Najjar, Orrin Devinsky Journal of Neuroinflammation 2013, 10:43 (1 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research   Open Access

Protective and therapeutic potency of N-acetyl-cysteine on propionic acid-induced biochemical autistic features in rats

Abeer M Aldbass, Ramesa Shafi Bhat, Afaf El-Ansary Journal of Neuroinflammation 2013, 10:42 (27 March 2013)

Abstract | Provisional PDF | PubMed

Research   Open Access

Dual effects of daily FTY720 on human astrocytes in vitro: relevance for neuroinflammation

Celina Wu, Soo Y Leong, Craig S Moore, Qiao Ling Cui, Pavel Gris, Louis-Philippe Bernier, Trina A Johnson, Philippe Séguéla, Timothy E Kennedy, Amit Bar-Or, Jack P Antel Journal of Neuroinflammation 2013, 10:41 (19 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

Short report   Open Access

Ghrelin inhibits LPS-induced release of IL-6 from mouse dopaminergic neurones

Amy L Beynon, M Rowan Brown, Rhiannon Wright, Mark I Rees, I Martin Sheldon, Jeffrey S Davies Journal of Neuroinflammation 2013, 10:40 (19 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

Case report   Open Access

Corticosteroid therapy in a patient with cerebral amyloid angiopathy-related inflammation

Akio Kimura, Takeo Sakurai, Nobuaki Yoshikura, Yuichi Hayashi, Masao Takemura, Hitoshi Takahashi, Takashi Inuzuka Journal of Neuroinflammation 2013, 10:39 (16 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research   Open Access

Plasma cytokine profiling in sibling pairs discordant for autism spectrum disorder

Valerio Napolioni, Benjamin Ober-Reynolds, Szabolcs Szelinger, Jason J Corneveaux, Traci Pawlowski, Sharman Ober-Reynolds, Janet Kirwan, Antonio M Persico, Raun D Melmed, David W Craig, Christopher J Smith, Matthew J Huentelman Journal of Neuroinflammation 2013, 10:38 (14 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research   Open Access Highly Accessed

Insulin-like growth factor 1 and 2 (IGF1, IGF2) expression in human microglia: differential regulation by inflammatory mediators

Hyeon-Sook Suh, Meng-Liang Zhao, Leandra Derico, Namjong Choi, Sunhee C Lee Journal of Neuroinflammation 2013, 10:37 (12 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research   Open Access

Amelioration of autoimmune neuroinflammation by the fusion molecule Fn14·TRAIL

Hodaya Prinz-Hadad, Tehila Mizrachi, Michal Irony-Tur-Sinai, Tatyana B Prigozhina, Alexandra Aronin, Talma Brenner, Michal Dranitzki-Elhalel Journal of Neuroinflammation 2013, 10:36 (9 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research   Open Access Highly Accessed

Macrophages in inflammatory multiple sclerosis lesions have an intermediate activation status

Daphne YS Vogel, Elly JF Vereyken, Judith E Glim, Priscilla DAM Heijnen, Martina Moeton, Paul van der Valk, Sandra Amor, Charlotte E Teunissen, Jack van Horssen, Christine D Dijkstra Journal of Neuroinflammation 2013, 10:35 (4 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

Correction   Open Access Highly Accessed

Correction: Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: evidence for an immune-modulated glutamatergic neurotransmission?

Johann Steiner, Martin Walter, Tomasz Gos, Gilles J Guillemin, Hans-Gert Bernstein, Zoltán Sarnyai, Christian Mawrin, Ralf Brisch, Hendrik Bielau, Louise M zu Schwabedissen, Bernhard Bogerts, Aye-Mu Myint Journal of Neuroinflammation 2013, 10:34 (2 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research   Open Access

TNF-α promotes cerebral pericyte remodeling in vitro, via a switch from α1 to α2 integrins

Ulrich Tigges, Amin Boroujerdi, Jennifer V Welser-Alves, Richard Milner Journal of Neuroinflammation 2013, 10:33 (1 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research   Open Access

In vivo temporal and spatial profile of leukocyte adhesion and migration after experimental traumatic brain injury in mice

Susanne M Schwarzmaier, Ricarda Zimmermann, Niamh B McGarry, Raimund Trabold, Seong-Woong Kim, Nikolaus Plesnila Journal of Neuroinflammation 2013, 10:32 (28 February 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research   Open Access

Transmigration of polymorphnuclear neutrophils and monocytes through the human blood-cerebrospinal fluid barrier after bacterial infection in vitro

Ulrike Steinmann, Julia Borkowski, Hartwig Wolburg, Birgit Schröppel, Peter Findeisen, Christel Weiss, Hiroshi Ishikawa, Christian Schwerk, Horst Schroten, Tobias Tenenbaum Journal of Neuroinflammation 2013, 10:31 (28 February 2013)

Abstract | Provisional PDF | PubMed

Short report   Open Access

Neuroprotective and antiepileptogenic effects of combination of anti-inflammatory drugs in the immature brain

Young Se Kwon, Eduardo Pineda, Stéphane Auvin, Don Shin, Andrey Mazarati, Raman Sankar Journal of Neuroinflammation 2013, 10:30 (26 February 2013)

Abstract | Full text | PDF | ePUB | PubMed

Reviewer acknowledgement   Open Access

Reviewer acknowledgement

Sue T Griffin, Robert E Mrak Journal of Neuroinflammation 2013, 10:17 (26 February 2013)

Abstract | Full text | PDF | ePUB | PubMed

Case report   Open Access

An autoinflammatory neurological disease due to interleukin 6 hypersecretion

Ettore Salsano, Ambra Rizzo, Gloria Bedini, Loris Bernard, Valentina Dall’Olio, Sara Volorio, Monica Lazzaroni, Isabella Ceccherini, Dejan Lazarevic, Davide Cittaro, Elia Stupka, Rosina Paterra, Laura Farina, Mario Savoiardo, Davide Pareyson, Francesca L Sciacca Journal of Neuroinflammation 2013, 10:29 (21 February 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research   Open Access Highly Accessed

Rosmarinic acid protects against experimental diabetes with cerebral ischemia: relation to inflammation response

Haiyun Luan, Zechun Kan, Yong Xu, Changjun Lv, Wanglin Jiang Journal of Neuroinflammation 2013, 10:28 (17 February 2013)

Abstract | Full text | PDF | ePUB | PubMed

Review   Open Access Highly Accessed

Toll-like receptor 4 signaling in intracerebral hemorrhage-induced inflammation and injury

Huang Fang, Peng-Fei Wang, Yu Zhou, Yan-Chun Wang, Qing-Wu Yang Journal of Neuroinflammation 2013, 10:27 (17 February 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research   Open Access

Treatment with an anti-CD11d integrin antibody reduces neuroinflammation and improves outcome in a rat model of repeated concussion

Sandy R Shultz, Feng Bao, Lynne C Weaver, Donald P Cain, Arthur Brown Journal of Neuroinflammation 2013, 10:26 (15 February 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research   Open Access

Complement activation fragment C5a receptors, CD88 and C5L2, are associated with neurofibrillary pathology

Maria I Fonseca, Susan O McGuire, Scott E Counts, Andrea J Tenner Journal of Neuroinflammation 2013, 10:25 (8 February 2013)

Abstract | Full text | PDF | PubMed

Research   Open Access

Cerebral ischemia initiates an immediate innate immune response in neonates during cardiac surgery

Selma O Algra, Kathelijne M Groeneveld, Alvin WL Schadenberg, Felix Haas, Fabiola CM Evens, Jenny Meerding, Leo Koenderman, Nicolaas JG Jansen, Berent J Prakken Journal of Neuroinflammation 2013, 10:24 (7 February 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research   Open Access Highly Accessed

Toll-like receptor 4 mediates microglial activation and production of inflammatory mediators in neonatal rat brain following hypoxia: role of TLR4 in hypoxic microglia

Linli Yao, Enci Mary Kan, Jia Lu, Aijun Hao, S Thameem Dheen, Charanjit Kaur, Eng-Ang Ling Journal of Neuroinflammation 2013, 10:23 (6 February 2013)

Abstract | Full text | PDF | ePUB | PubMed

Short report   Open Access

Interleukin-10 modulates the synthesis of inflammatory mediators in the sensory circumventricular organs: implications for the regulation of fever and sickness behaviors

Lois M Harden, Christoph Rummel, Giamal N Luheshi, Stephen Poole, Rüdiger Gerstberger, Joachim Roth Journal of Neuroinflammation 2013, 10:22 (6 February 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research   Open Access

Hypothermia enhances induction of protective protein metallothionein under ischemia

Youn Hee Park, Young Mi Lee, Dong Sun Kim, Jaechan Park, Kyoungho Suk, Jong Kun Kim, Hyung Soo Han Journal of Neuroinflammation 2013, 10:21 (4 February 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research   Open Access

Molecular evidence for the involvement of PPAR-δ and PPAR-γ in anti-inflammatory and neuroprotective activities of palmitoylethanolamide after spinal cord trauma

Irene Paterniti, Daniela Impellizzeri, Rosalia Crupi, Rossana Morabito, Michela Campolo, Emanuela Esposito, Salvatore Cuzzocrea Journal of Neuroinflammation 2013, 10:20 (1 February 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research   Open Access

MyD88 is crucial for the development of a protective CNS immune response to Toxoplasma gondii infection

Marbel Torres, Rachel Guiton, Sonia Lacroix-Lamandé, Bernhard Ryffel, Samuel Leman, Isabelle Dimier-Poisson Journal of Neuroinflammation 2013, 10:19 (1 February 2013)

Abstract | Full text | PDF | ePUB | PubMed

Correction   Open Access

Correction: Transcriptomics and proteomics analyses of the PACAP38 influenced ischemic brain in permanent middle cerebral artery occlusion model mice

Motohide Hori, Tomoya Nakamachi, Randeep Rakwal, Junko Shibato, Tetsuo Ogawa, Toshihiro Aiuchi, Tatsuaki Tsuruyama, Keiji Tamaki, Seiji Shioda Journal of Neuroinflammation 2013, 10:18 (31 January 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research   Open Access Highly Accessed

Activation of microglial cells triggers a release of brain-derived neurotrophic factor (BDNF) inducing their proliferation in an adenosine A2A receptor-dependent manner: A2A receptor blockade prevents BDNF release and proliferation of microglia

Catarina Gomes, Raquel Ferreira, Jimmy George, Rui Sanches, Diana I Rodrigues, Nélio Gonçalves, Rodrigo A Cunha Journal of Neuroinflammation 2013, 10:16 (30 January 2013)

Abstract | Full text | PDF | ePUB | PubMed

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