A) Representative images of the dentate gyrus of hippocampus showing immunoreactivity for Iba1. A) Non-stressed female treated with vehicle; B) Prenatally stressed female treated with vehicle; C) Non-stressed female treated with LPS and D) Prenatally stressed female treated with LPS. Inserts show details of the morphology of Iba1-immunoreactive cells at high magnification. Scale bar, 50 μm. In the inserts, the scale bar represents 7.5 μm. B) Number of Iba1-immunoreactive cells/mm3 in the hilus of dentate gyrus of hippocampus. NS, non-stressed female mice; PS, prenatally stressed females. Filled bars, animals treated with vehicle (VEH). Empty bars, animals treated with LPS. Data are mean ± SEM. *, Significant differences (P <0.05) versus NS-VEH. aSignificant difference (P <0.05) versus NS-VEH and PS-VEH mice. bbSignificant difference (P <0.01) versus NS-VEH and PS-LPS.
Diz-Chaves et al. Journal of Neuroinflammation 2012 9:71 doi:10.1186/1742-2094-9-71