Table 10

Frequency of supratentorial and infratentorial brain involvement.

Seropositive

(No of patients, %)

Seronegative

(No of patients, %)

p-level

Supratentorial brain lesions at first MRI

Total cohort

63/133 (47.4)^†

16/35 (45.7)^†

n.s.^‡

Patients meeting Wingerchuk's 2006

criteria

38/89 (42.7)

13/26 (50)

n.s.^‡

Supratentorial brain lesions ever

Total cohort

78/133 (58.7)

21/36 (58.3)

n.s.^‡

Patients meeting Wingerchuk's 2006

criteria

51/89 (57.3)

16/27 (59.3)

n.s.^‡

Brain stem involvement^#

Total cohort

39/137 (28.5)

7/38 (18.4)

n.s.^‡

Patients meeting Wingerchuk's 2006

criteria

31/92 (33.7%)

7/27 (25.9%)

n.s.^‡

^†Considered "compatible with MS" by the reading radiologists in 11 cases (8.9%) in the seropositive group and in 3 cases (9.4%) in the seronegative group (p = n.s.). ^#Clinical and/or MRI evidence. ^‡Fisher's exact test (2-tailed).

Jarius et al. Journal of Neuroinflammation 2012 9:14   doi:10.1186/1742-2094-9-14