Figure 8.

Proposed model to illustrate the signaling pathways involved in MMP-9 expression in RBA-1 cells infected with JEV. JEV-induced MMP-9 expression is mediated through ROS/c-Src/PDGFR/PI3K/Akt/MAPKs leading to AP-1 activation in RBA-1 cells.

Yang et al. Journal of Neuroinflammation 2012 9:12   doi:10.1186/1742-2094-9-12
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