Research
Signal pathways in astrocytes activated by cross-talk between of astrocytes and mast cells through CD40-CD40L
Department of Pharmacology and Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, 300 chunchun-dong, Jangan-ku, Suwon, 440-746, South Korea
Journal of Neuroinflammation 2011, 8:25 doi:10.1186/1742-2094-8-25
Published: 16 March 2011Additional files
Additional file 1:
Figure S1. Intracellular Ca2+ level, surface molecules or cytokine mRNA expression in co-cultured-astrocytes.
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Additional file 2:
Figure S2. CD40 siRNA transfection or time courses for activities of Rho family GTPases, PKC isoforms or MAP kinases in co-cultured-astrocytes.
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Additional file 3:
Figure S3. Time courses for activities of transcription factors or effects of inhibitors on activities of PKC isoforms or MAP kinases in co-cultured-astrocytes.
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Additional file 4:
Figure S4. Effects of inhibitors on activities of transcription factors or expressions of cytokine mRNA in co-cultured-U87 cells.
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Additional file 5:
figure S5. Effects of anti-TNFR1 antibody pretreatment on the co-cultured-U87 cells.
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Additional file 6:
Figure S6. Infiltration of inflammatory cells and co-localization of TNFR1 and mast cells in EAE-induced mouse brain.
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