Table 2 |
||
|
Microarray studies of microglia transduced with Ad-IRF3 or Ad-GFP and stimulated with IL-1/IFNγ: |
||
|
Gene |
Ratio (IRF3/GFP) |
Difference in expression (IRF3 minus GFP) |
|
|
||
|
IFNB (IFNβ) |
3.5 |
418 |
|
IRF7 |
2.3 |
1441 |
|
IFIT1 |
11.2 |
4464 |
|
SOCS1 |
2.6 |
776 |
|
IL-1A (IL-1α) |
0.2 |
-708 |
|
IL-1B (IL-1β) |
0.1 |
-4738 |
|
IL-1RN (IL-1ra) |
6.4 |
2211 |
|
IL-10 |
1.9 |
364 |
|
IL-10RA (IL-10R) |
2.4 |
1145 |
|
IL-27 |
1.8 |
250 |
|
IL-8 |
0.3 |
-15409 |
|
CXCL1 |
0.5 |
-167 |
|
|
||
|
Human fetal microglia were transduced with adenovirus for 2 days and further treated with IL-1/IFNγ for 16 h. Microarray was performed using the Illumina platform. |
||
|
Tarassishin et al. Journal of Neuroinflammation 2011 8:187 doi:10.1186/1742-2094-8-187 |
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