OX-42 (Aa, Ba, Ca) and IL-1β (Ab, Bb, Cb) expression in 5-d-old rats receiving saline, LPS or DMS + LPS injections and sacrificed 1 h later. The intensity of IL-1β immunoexpression in AMC is significantly enhanced in LPS-injected rats (Ba-c) when compared with control rats (Aa). Upregulated IL-1β immunoexpression in AMC appears to be sustained in DMS + LPS-injected rats (Ca). Co-expression of OX-42 and IL-1β is evident in DMS + LPS rats as seen in merged images in Cc (arrows). Nuclei are stained with DAPI. Scale bar = 50 μm.
Lin et al. Journal of Neuroinflammation 2011 8:13 doi:10.1186/1742-2094-8-13