Figure 1.

Pre-treatment with IFN-γ reduces the survival of neurons incubated with amyloid-β_1-42. The survival of primary cortical neurons pre-treated with 1 ng/ml TNFα, IL-1β, IL-6 or IFN-γ prior to the addition of 10 μm amyloid-β_1-42 (shaded bars) or 10 μm amyloid-β_42-1 (open bars). Values shown are the mean percentage cell survival from triplicate experiments repeated 3 times (n = 9), ± standard deviation (SD). ** = Neuronal survival significantly less than untreated neurons incubated with amyloid-β_1-42 (p < 0.05).