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Associations of AD with HLA-B7 and HLA-Cw*0702 by zygosity |
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| Allele |
Homozygotes/heterozygotes/negatives(n) |
Unadjusted† odds ratios of AD (95% CI, p) (versus negatives) |
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| Controls |
AD |
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| HLA-B7 |
0/42/157 |
7/58/131 |
Heterozygotes: 1.7 (1.02–2.7, 0.04) |
| Homozygotes: 18.0 (1.6–202, 0.0045) |
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| HLA-Cw*0702 |
1/46/152 |
9/58/128 |
Heterozygotes: 1.5 (0.9–2.4, 0.09) |
| Homozygotes: 10.7 (1.6–72.0, 0.007) |
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AD = Alzheimer's disease, CI = confidence interval. †Analyses were unadjusted since there were too few homozygotes for regression analysis | |||
Lehmann et al. Journal of Neuroinflammation 2006 3:33 doi:10.1186/1742-2094-3-33 |
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